Akari Therapeutics Releases New CEO Corner Segment Highlighting 2025 Progress and Path to Clinical Transition In 2026
01/09/2026 09:00 AM • Akari Therapeutics announced progress in 2025 and outlined its path toward clinical transition in 2026. The company established a manufacturing partnership with WuXi Biologics and initiated pre-filing activities, with plans to launch its First-in-Human clinical trial by late 2026/early 2027. The company's lead candidate AKTX-101 is an ADC targeting Trop2 with a novel PH1 spliceosome-modulating payload designed to deliver dual mechanisms of action: direct tumor cytotoxicity and immune activation.
AKTX - Company achieved key milestones in 2025 including manufacturing partnership with WuXi Biologics, initiated CMC activities, and is on track for clinical trial initiation by late 2026/early 2027. Preclinical data shows promising efficacy and safety profile for lead candidate AKTX-101 with potential synergy with checkpoint inhibitors.