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News  ›  Benzinga

Precision Killers: Why Big Pharma is Betting Billions to Beat a $170B Patent Cliff

Benzinga Logo Benzinga By Prnewswire
Precision Killers: Why Big Pharma is Betting Billions to Beat a $170B Patent Cliff

The precision oncology market is projected to grow from $110 billion to $225.65 billion by 2032, driven by Big Pharma's race to acquire registration-ready assets ahead of a $170 billion patent cliff through 2030. Several biotech companies are advancing promising clinical programs: Oncolytics Biotech strengthened its leadership team for pelareorep development in gastrointestinal cancers; Nurix is executing pivotal studies for its BTK degrader bexobrutideg in chronic lymphocytic leukemia; Erasca reported early clinical data for its pan-RAS molecular glue ERAS-0015; Foghorn raised $50 million for its SMARCA4-targeting program; and ORIC presented strong Phase 1b data for rinzimetostat in prostate cancer.

Insights
LRCX   positive

Delivered 107% return and showed stronger market performance compared to Applied Materials


ONCY   positive

Company strengthened executive leadership with experienced oncology trial executives, advanced pelareorep toward registration with compelling clinical data (29-30% response rates in anal cancer, FDA alignment on pancreatic cancer Phase 3), and expanded scientific advisory board with top-tier cancer center experts.